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EPAC2 protein not only serves as a key intracellular effector of cAMP but also acts as an upstream activator of the small GTPase RAP1, as supported by our RNA sequencing data (Fig

In addition, LSH can activate genes related to glucose transporter (GLUTs) and fatty acid dessaturase (FADSs), and affect the metabolism of lung cancer cells

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[DOI] [PMC free article] [PubMed] [Google Scholar] 166.Iciek M., Grny M., Kotaska M., Bilska-Wilkosz A., Kaczor-Kamiska M., Zagajewski J